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FIGURE 8
Figure 8. Reduced 26S proteasome activity was detected in U-box− /− fish. (A) Chymotrypsin-like activity was measured in brain tissues of U-box− /− and wild-type fish at 6 and 24 months (n = 4). Statistically significant differences are shown by asterisks (∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001, Student’s t-test). (B) Oligomer expression quantified from dot blot analysis in brain tissues of U-box− /− and wild-type fish at 6 and 24 months (n = 3). Data shown are means and error bars indicate standard deviations.
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Full text @ Front. Mol. Neurosci.