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Zhao et al., 2021 - The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway

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Fig. 1 Decreased HSPCs in the CHT region of zebrafish <italic>smu471</italic> mutants.

A–Dcmyb WISH identified HSPCs from 2 to 4 dpf in smu471 mutants (right) compared with their siblings (left). Acmyb⁺ signals were not altered at 2 dpf in the VDA region (blue arrowheads indicate signals in the region). B In the CHT region, cmyb⁺ signals were decreased slightly at 2.5 dpf in smu471 mutants (red arrowheads indicate signals in the region). C, D Severely decreased cmyb⁺ signals in the CHT region at 3 dpf (C) with a further reduction at 4 dpf (D) in smu471 mutants. The boxed regions in the lower right corner are magnifications. Scale bars: 200 µm.

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