Figure 1

Figure 1

Vascular organization of intact caudal fin vs. early regeneration. Organization of tissue compartments in the intact caudal fin (a) versus the regenerating fin (b), at 7dpa. a/a’ display smooth and hierarchically well-organized blood vessels (green - reporter transgenic zebrafish line) in which intraray segments do not contain any vessels (asterisk) and capillary sprouts are not detectible (a’). (b/b’) display dense, well-interconnected capillary meshwork. The intraray region (purple asterisks) contains bridging vessels and at the expanding vascular front multiple sprouts (b’, white arrows) and migrating - endothelial cells (purple arrows). Images are acquired by fluorescent reflected light microscope.