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FIGURE 6
Figure 6. Diphtheria toxin induced hair cell death is primarily due to apoptosis. (A) Saccule and utricle from WT and Tg(myo6b:hDTR) (hDTR) inner ear tissues 2 days post-DT. Hair cells are labeled with phalloidin (green channel) and cleaved caspase-3 (red channel) positive cells were detected 2 days post-DT. (B) Quantification of cleaved caspase-3 positive cells in saccule and utricle dissected on days 1?5 following DT injection. Scale bar 100 ?m. For qualitative purposes, brightness and contrast increased by 20%.
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Full text @ Front. Cell. Neurosci.