IMAGE

FIGURE 2

ID

ZDB-IMAGE-210902-26

Genes

mCherry

Publication

Koh et al., 2021 - Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy

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Figures for Koh et al., 2021

Image

Figure Caption

FIGURE 2

Expression and diffusion coefficients of FPs and FP-tagged Smn in zebrafish motor neurons. (A) Expression of eGFP, eGFP-Smn, mCherry, and mCherry-Smn in cell body and axon of motor neurons at 2 dpf. Images of cell body and axon are taken from different motor neurons. Scale bar = 5 μm. Red arrow indicates representative position where FCS measurement was taken in axon. (B) Average diffusion coefficients, D₁ (μm²/s) of eGFP, eGFP-Smn, mCherry, mCherry-Smn in cell body. (C) Average diffusion coefficients, D₂ (μm²/s) of eGFP-Smn, mCherry-Smn in cell body. (D) Average diffusion coefficients, D₁ (μm²/s) of eGFP, eGFP-Smn, mCherry, mCherry-Smn in axons. (E) Average diffusion coefficients, D₂ (μm²/s) of eGFP-Smn, mCherry-Smn in axons. Error bars represent the SD. (^n.s.P > 0.05, *P < 0.05). The numbers above the graph indicate the numbers of fish (number of points) the measurements were taken in.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol