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Figure 2

ID: ZDB-IMAGE-210822-11
Publication: Holmgren et al., 2021 - Influence of Mpv17 on Hair-Cell Mitochondrial Homeostasis, Synapse Integrity, and Vulnerability to Damage in the Zebrafish Lateral Line
All Figures: Figures for Holmgren et al., 2021

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Figure Caption

Figure 2

mpv17^a9/a9 hair cells have hyperpolarized mitochondria. (A–C, E–G) Maximum-intensity projections of confocal images displaying WT (A–C) and mpv17^a9/a9(E–G) neuromasts with DAPI-labeled hair cells (A–E) and staining with MitoTracker Red CMXRos (B–F) and MitoTracker Deep Red (C–G). (D–H) Mean intensities for both MitoTracker Red CMXRos (D) and MitoTracker Deep Red (H) are elevated in mpv17^a9/a9 neuromasts (*P = 0.0469; ****P < 0.0001). n = 29–31 neuromasts (L3, L4, and L5); N = 4 experimental trials. Scale bar: 5 μm. Error bars: SEM.

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