ZFIN Image: Bohaud et al., 2021, Figure 2

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Figure 2

Caudal fin regeneration under infectious conditions. Amputation of the caudal fin in an infectious condition, with a scalpel pre-soaked in a solution containing pathogenic microorganisms (for instance Listeria monocytogenes) impairs tissue regeneration. Exacerbated inflammation is caused by an excessive number of tnfa-positive MФ at the wound. Resolution of inflammation is impeded at 24 hpa, with many tnfa-positive MФ that remain present. This results in incomplete tissue restoration and fibrosis at 7 dpa onward, characterized by the presence of disorganized collagen fibers.

Acknowledgments

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