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Fig. 4 (A) The fraction of ROIs per frequency at the whole-brain (WB) and regional levels. Remaining brain regions now shown here can be found in Figure S2. (B–G) The spatial distribution of ROIs from the dorsal (top left) and lateral (top right) views are shown. Bar graphs (bottom left) show the proportions of nearest neighbors for ROIs of a given frequency preference (separate bars for ROIs responding to different frequencies), with same-frequency neighbors indicated by a black box. For comparison, data from the spatially randomized dataset are shown in the last bar. Matrices (bottom right) of the neighbor frequency index show pairs of frequencies that are overrepresented (blue, bar in B) or underrepresented (red) as neighbors. Significant results versus the randomized dataset are indicated (⋅p < 0.05; ⋅⋅p < 0.01; ⋅⋅⋅p < 0.001; ⋅⋅⋅⋅p < 0.0001). See Figure S3 for p values. Kruskal-Wallis tests with Dunn’s correction for multiple comparisons were performed to establish p values. The k-nearest neighbor heatmap legend is shown in (B) and applies to (B)–(G). The same information for the remaining brain regions can be found in Figure S2, and all p values are presented in Figure S3. Figure S4 shows additional whole-brain responses to logarithmic frequencies from 251 to 1,998 Hz at the original volume and 3 lower volumes, −6, −12, and −18 dB below. Scale bars represent 50 μm.