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FIGURE 2 CDDP, DXT, and Dox dosing in zebrafish. (A) zCDXs engrafted SGC7901 cells (dyed with red fluorescence using DiL) were treated with CDDP, DXT, or Dox at their 1/4, 1/2, and 1 MTD, and they inhibited cell proliferation in a dose-dependent manner (control-1, embryo medium for CDDP assay; control-2, embryo medium containing 0.1% DMSO for DXT or Dox assay) (*P < 0.05, **P < 0.01 vs. control-1 or control-2). (B) A protocol for preclinical chemosensitivity test in the zebrafish larvae cancer model was developed.
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Full text @ Front Cell Dev Biol