Image
|
Figure Caption
Figure 1 foxm1 CRISPR/Cas9-mediated disruption results in in-frame deletions. (A) The genomic sequence of foxm1 highlighting the 5′ and 3′ UTRs (yellow boxes), exons (black boxes) and regions targeted with CRISPR/Cas9. This strategy targets the NRD and the TAD domains. (B) Statistically significant deletions (p value < 0.05) detected at 24 hpf in batches of 8 embryos injected with sgRNA 8.2. Frequency reflects abundancy of WT and mutant alleles. n = 5.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Cells