ZFIN Image: Mannucci et al., 2021, Fig. 4

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Figure Caption

Fig. 4

Protein variants of DHX30 lead to embryonal developmental defects in zebrafish. In vivo analyses of selected DHX30 missense variants. Assessment of embryonic development after injection of DHX30 WT and mutant cDNAs in a zebrafish model. Bar graph indicating the percentage of cmcl2-GFP positive zebrafish embryos assessed 4–7 days post fertilization (dpf). The presented data are derived from three independent studies. The total number of embryos assessed are 45, 23, 21, 30, 34, 33, and 29 for WT, V556I, E948K, R493H, R725H, R785C, and R908Q, respectively. ****: significantly different from WT (****p< 0.0001; χ² test)

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