ZFIN Image: Knickmeyer et al., 2021, Figure 2

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Figure Caption

Figure 2 Ubiquitous bmp4 induction, but not eye specific bmp4 expression, results in a midline defect. (A–C) Immunohistochemistry against GFP in (B,C) tg(pou4f3:mGFP, rx2:bmp4) embryos and (A) controls at 4 dpf. Chiasms are intact, but optic nerve trajectories are irregular (arrows). (D–K) Immunohistochemistry against Ac-αTub and GFAP in (E,G,I,K) tg(hsp70l:bmp4) embryos and (D,F,H,J) controls at 25–45 hpf reveals the anterior (asterisks) and post-optic (arrowheads) commissures. Later stages include optic nerves (arrows). All images are maximum intensity projections, transverse view, scale bars 50 µm.

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.