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Fig. 3 Effects of phloroglucinol (PG) and dieckol (DK) on the migration of EA.hy 926 cells treated with a high concentration of glucose. (A) Images were acquired at the initial gap length (0 h) and final gap length (4 h) following treatment with PG in the cell-migration assay. (a) 0 mM glucose + 0 µM PG; (b) 30 mM glucose + 0 µM PG; (c) 30 mM glucose + 0.8 µM PG; (d) 30 mM glucose + 2.4 µM PG; and (e) 30 mM glucose + 8 µM PG; Quantitative evaluation of the inhibition of migration of EA.hy926 cells treated with a high glucose concentration after treatment with PG. (B) (a) 0 mM glucose + 0 µM DK; (b) 30 mM glucose + 0 µM DK; (c) 30 mM glucose + 0.1 µM DK; (d) 30 mM glucose + 0.3 µM DK; and (e) 30 mM glucose + 1 µM DK; Quantitative evaluation of the inhibition of migration of EA.hy926 cells treated with high glucose concentration after treatment with DK. The effect of 30 mM of glucose was compared to that of B; blank (0 mM glucose + 0 μM PG), ### p < 0.001. Percentage gap closure was normalized to that of C: control (30 mM glucose + 0 μM PG); ns, not significant, ** p < 0.01, *** p < 0.001.