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Figure 1; supplement 3.

ID: ZDB-IMAGE-210208-69
Publication: Alyenbaawi et al., 2021 - Seizures are a druggable mechanistic link between TBI and subsequent tauopathy
All Figures: Figures for Alyenbaawi et al., 2021

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Figure Caption

Figure 1; supplement 3. Movement of some Tau puncta over time following injection of zebrafish larvae with brain homogenate burdened with human tauopathy.

(A) Images of the zebrafish brain area, after injection with Tg hTau^+/p301L mouse brain homogenate, for the same zebrafish larvae over 3 consecutive days post-injection (dpi), showing the movement of one puncta over time. (B, B’ and B”) The location of Tau aggregates on the spinal cord of three exemplar individual larvae over multiple days, denote movement of some of these puncta over time. Somite numbers were used as landmarks to report the location along the spinal cord over multiple days - somites are blocks of tissue (e.g. muscle) that are readily visible in the trunk of the larva; larger somite number are more posterior (i.e. more distal to the injected brain region) with the most distal region being ‘unsegmented’.

Acknowledgments

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