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Figure 6

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ZDB-IMAGE-201213-7
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Figures for Oel et al., 2020
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Figure Caption

Figure 6

Rod Outer Segments of nrl−/− Adult Zebrafish Appear Normal

(A) Rods demonstrate the expected hairpin end of floating disks within the outer segment that are non-contiguous with the outer cell membrane (A′), diagnostic of rod cell identity

(B) In wild-type adult zebrafish, photoreceptor synaptic terminals include rod spherules (teal dotted line) that are morphologically distinguishable from cone pedicles (yellow).

(C) In nrl−/− adult retina, the cone pedicles appear normal, and rod spherules appear normal but are very sparse; instead, electron-lucent terminals (white arrows) uniquely appear and may represent an Nrl-dependent defect in rod synapse maintenance. Various characters of photoreceptor terminals are quantified in Figure S6. Mt, mitochondria; Ms, melanosomes.

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Acknowledgments
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