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Fig 6

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Publication: Colucci-Guyon et al., 2020 - Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system
All Figures: Figures for Colucci-Guyon et al., 2020

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Figure Caption

Fig 6 ML is detected in the brain of <italic>M</italic>. <italic>ulcerans</italic> infected mice.

(A) UHPLC elution profiles obtained after elution of spleen (left panels) or brain (right panels) lipid extracts from non-infected (Control) or M. ulcerans-infected mice. Lipid extracts have been prepared from pools of 6 organs. For each UHPLC profile are shown the total ion current (top) and ML’s ion extract [M+Na]+ = 765.4913 (bottom). (B) MS/MS ML’s spectrum showing parental (PI) and fragmentation ions (stars) for pure (top) or ML identified in brain’s lipid extract of M. ulcerans infected mice.

Acknowledgments

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