ZFIN Image: Eufrásio et al., 2020, Figure 8

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Figure Caption

Figure 8

Theoretical model of the functional domains of seq132. Schematic representation from the three possible sequence versions and the respective associated enhancer activity level: high (A), low (B), and no enhancer activity (C). The gene SLC30A08 is represented in blue. The symbol # represents common variants with no association with type 2 diabetes. The wt and risk alleles are represented in black boxes, the putative repressor in red, and the binding site for PDX1 in green. The dashed line shows interdependence.

Acknowledgments

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