Figure 2—figure supplement 2.

Figure 2—figure supplement 2.

The detailed view of positions 396–576 of OG_28197 (top; 648 AA alignment with 34 sequences from 22 deuterostomes and 8 lophotrochozoans) and of positions 174–354 of OG_33174 (bottom; 430 AA alignment with 29 sequences from 24 deuterostomes and 4 lophotrochozoans) illustrates the existence of domain-like conservation patterns despite the absence of known protein domains. Coloured blocks indicate sequences of lophotrochozoan (L) and deuterostome (D) origin. The two displayed alignments lack ecdysozoan sequences; they were chosen for their small size and convenient presentation. Short stretches of unaligned sequences were removed for clarity. Dashes indicate sequence gaps. Colouring of amino acids reflects chemical similarity (UGENE standard colour scheme; Okonechnikov et al., 2012). Bar chart on top displays sequence conservation of alignment columns beneath.