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Fig. EV5

ID: ZDB-IMAGE-201012-116
Publication: Pini et al., 2020 - ALX1-related frontonasal dysplasia results from defective neural crest cell development and migration
All Figures: Figures for Pini et al., 2020

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Fig. EV5 Qualitative and quantitative characterization of zebrafish mutants

The number of embryos displaying craniofacial phenotypes increased with increasing concentration of Alx1DN mRNA injected into the single cell stage embryo. Overview of the relationship of the results of injections of 25, 50, and 100 pg of control mRNA and Alx1DN mRNA with the outcomes of wild‐type zebrafish (green), a craniofacial phenotype (gray), and dead zebrafish (magenta).

The number of embryos displaying craniofacial phenotypes injected with alx1^uw2016 mRNA was very low. Overview of the percent of injected wild‐type zebrafish displaying a craniofacial phenotype (gray), compared with uninjected wild‐type zebrafish from the identical clutches (gray). Data of the injections are presented as a comparative percentage.

Acknowledgments

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