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Fig. 7.

ID: ZDB-IMAGE-201003-122
Source: Figures for Hoeksma et al., 2020

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Figure Caption

Fig. 7.

Cercosporamide inhibits kinase activity of purified ALK receptors in vitro. (A) IC50 values of cercosporamide-mediated inhibition of a panel of ten kinases. (B-K) Activity graphs from which the IC50 values in A were derived. The kinases include six type I ALK BMPRs, mitogen-activated protein kinase (MAPK)-interacting protein kinases 1 and 2 (MNK1, MNK2), mitogen-activated protein kinase kinase (MEK) and the tyrosine kinase, anaplastic lymphoma kinase (ALK). wt, wild type.

Acknowledgments

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