ZFIN Image: Yang et al., 2020, Figure 2-S4

Image

Figure Caption

Figure 2-S4 Blocking circulation by a morpholino-mediated <italic>tnnt2</italic> knockdown prevented macrophage infiltration into the liver 8 hr after brain injection with LPS.

(a) Representative 3D volumetric and single z-plane images shown for after LPS or water vehicle injection in the brain. Dotted region shows liver in the single channel panels. Transgenes fabp10a:DsRed and mpeg1:GFP were used to label hepatocytes and macrophages, respectively. (b) Quantification of the number of macrophages found in the liver at 8hpi in four dpf zebrafish. No difference was found between the control and LPS injected groups as they both lacked macrophage infiltration. Each symbol represents an independent animal. Statistical test was determined by a two-tailed t-test. ns, not significant; MO, morpholino.

Acknowledgments

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