ZFIN Image: Lee et al., 2020, Figure 8

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Figure Caption

Figure 8

Synergistic effects of methiothepin treatment on paclitaxel sensitivity in ES2 and OV90 cells. (A) Hoechst (blue) and PI (red) staining analysis of ES2 and OV90 cells after combination treatment with methiothepin and paclitaxel. Scale bar indicates 40 μm. (B) Analysis of the viabilities of ES2 and OV90 cells revealed that methiothepin and paclitaxel are synergistic in inhibiting the viability of these cells. (C) The synergistic effects of the combination of methiothepin and paclitaxel on the viability of ES2 and OV90 cells were calculated based on the combination index (CI) and fraction affected (FA) using the CompuSyn software. Results are expressed as the means ± SDs of three independent experiments. The asterisks indicate statistically significant differences compared to the control (* p < 0.05; ** p < 0.01; *** p < 0.001).

Acknowledgments

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