ZFIN Image: Lee et al., 2020, Figure 4

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Figure 4

Effect of methiothepin on mitochondrial membrane potential (ΔΨ) and mitochondrial Ca²⁺ levels in ES2 and OV90 cells. (A) The change in ΔΨ by methiothepin in ES2 and OV90 cells was analyzed by JC-1 staining. The degree of depolarization of the mitochondrial membrane was determined based on JC-1 green/red ratio. (B) The change of mitochondrial Ca²⁺ levels in ES2 and OV90 cells following methiothepin treatment was analyzed by staining with the Rhod-2 dye. Results are expressed as the means ± SDs of three independent experiments. The asterisks indicate statistically significant differences compared to the control (* p < 0.05; ** p < 0.01; *** p < 0.001).

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