ZFIN Image: Angileri et al., 2020, Figure S4

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Figure Caption

Figure S4

Loss of dnmt1 function results in misregulation of LTR RE expression across numerous tissues. A-X. Transverse cryosections of larvae analyzed by in situ hybridization. All sibling and dnmt1^-/- larvae are 4dpf. A-H. Expression of indicated REs within the lower jaw. I-N. Expression of indicated REs within the upper jaw. O-P. Expression of ERV1-N5 LTR in photoreceptors (O; sibling) and the RPE (P; dnmt1^-/-). Q-R. Expression of Bel20 LTR within the brain. S-X. Expression of indicated REs within the cornea. Arrows delineate expression changes of specified REs. Scale bar (A) = 10 μm. All images taken at the same magnification. RPE = retinal pigmented epithelium.

Acknowledgments

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