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Figure 6

ID: ZDB-IMAGE-200725-25
Publication: Toms et al., 2020 - Clinical and preclinical therapeutic outcome metrics for USH2A-related disease
All Figures: Figures for Toms et al., 2020

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Figure 6

Visual function in ush2a^u507 zebrafish. (A) Normalized average b-wave amplitude of ERG responses recorded from wt and ush2a^u507 zebrafish at 5 days post fertilization (wt: n = 69, ush2a^u507: n = 67). (B) Maximum b-wave amplitudes are plotted as bar graphs (mean ± SEM). (C) Visual acuity (cycles per degree, cpd) of wt and ush2a^u507 zebrafish at 3 months post fertilization (mpf), 6 mpf and 12 mpf, assessed using the optokinetic response assay (n = 4–5, mean ± SEM). ^*^*P < 0.001. Mann Whitney tests and two-way ANOVA were used to test for statistical significance in ERG and optokinetic response data, respectively.

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Phenotype details

Acknowledgments

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