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Figure 6

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Publication: Gans et al., 2020 - Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity
All Figures: Figures for Gans et al., 2020

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Figure 6

Identification and analysis of a common set of genes upregulated by chronic cortisol treatment in multiple RNA-seq experiments. (A) Venn diagrams showing numbers of upregulated and downregulated genes following reanalysis of the data from all three experiments and their overlap. Only 8 of the 12 genes in common between all experiments were annotated with gene names (listed). (B) Violin and box plots of estimated fold change of the 149 genes that are upregulated in at least 2 of the three experiments shown in (A); the differences between each experiment are statistically significant (Table S14). (C) Treemap generated by REVIGO⁵⁷ (https://revigo.irb.hr/) of GO biological process terms found by GOrilla³⁴ to be associated with the 149 genes upregulated by chronic cortisol treatment in at least two out of the three experiments.

Acknowledgments

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