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Figure 8

ID: ZDB-IMAGE-200713-19
Publication: Angileri et al., 2020 - dnmt1 function is required to maintain retinal stem cells within the ciliary marginal zone of the zebrafish eye
All Figures: Figures for Angileri et al., 2020

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Figure 8

RSCs require dnmt1 function to repress L1RE3-EGFP transposition. A–D Transverse sections of Tg(CMV:Hsa.L1RE3, EGFP, myl7:EGFP; dnmt1^+/+) (A, B) and Tg(CMV:Hsa.L1RE3, EGFP, myl7:EGFP; dnmt1^−/−) (C, D) larvae at 3dpf (A, A′, C, C′) and 4dpf (B, D). Nuclei labeled with DAPI (gray). Endogenous EGFP expression activated after L1RE3-EGFP transposition labeled in green. Arrows delineate EGFP + cells. Scale bars: 30 μm. Dorsal is up in all images.

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