ZFIN Image: Nadar et al., 2020, Fig. S5

Image

Figure Caption

Fig. S5

Ototoxicity assay in zebrafish embryos. A) Embryos were treated with PtPP (20 μM and 30 μM) and Cisplatin (positive control, 30 μM) and lateral line neuromasts were stained using DASPEI. Live imaging of these treated, stained embryos showed ototoxic effect of PtPP on the neuromast cells as expressed by a reduced amount of these cells caused by 30 μM of PtPP and cisplatin treatments after 2 days post treatment (neuromast cells indicated with white arrowheads). B) Quantification of the lateral line neuromast cells stained by DASPEI after 2 days post treatment with PtPP and cisplatin. Treatment using 30 μM cisplatin and 30 μM PtPP caused a significant reduction of neuromast cells. The plot represents means ± sem. **0.001 <P < 0.01; ****P <0.0001.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nanoscale