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Fig. s4 a. Comparison of integrated mean fluorescence at the focus of infection in animals treated with vehicle alone (0.5% DMSO) or 1 μM ezetimibe in vehicle. The focus of infection was defined as the region of macrophage accumulation at the site of infection. The mean fluorescence of Nile red signal was determined by drawing a region around the macrophage accumulation and then measuring Nile red fluorescence signal within this region and calculating mean fluorescence. Animals treated with ezetimibe showed reduced accumulation of Nile red signal at the focus of infection by comparison of mean fluorescence by Student’s t-test, p = 0.0076.