IMAGE

Figure 1

ID
ZDB-IMAGE-200511-18
Publication
Volpatti et al., 2020 - Identification of drug modifiers for RYR1 related myopathy using a multi-species discovery pipeline
All Figures
Figures for Volpatti et al., 2020
Image
Figure Caption

Figure 1 Schematic of our multi-species translational pipeline aimed at identifying potential therapeutic targets for RYR1-RM.

The pipeline involved screening C. elegans and zebrafish with thousands of compounds for suppressors of RYR1 mutant phenotypes, followed by further characterization in zebrafish and evaluation in mammalian cell lines.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife
Your Input Welcome
We welcome your input and comments. Please use this form to report issues or recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.