ZFIN Image: Tessadori et al., 2019, Fig. 2

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Fig. 2

The K91E substitution on HIST1H4J induces early severe developmental defects in zebrafish embryos. a Phenotypes observed in zebrafish embryos at 28 h post fertilization. Wildtype HIST1H4J (WT) and K91E mRNA was microinjected at the 1-cell stage. Class 1 embryos display normal development, class 2 embryos display mild shortening of the body axis and delayed head development. Class 3 embryos have severely defective head development and a shortened AP body axis, with abnormal posterior development. In Class 4 embryos head structures and somites are largely absent. b Histogram presenting the percentage of observed embryos in each class for each category. no inj non-injected control. The data presented were collected over three independent biological and technical experimental replicates

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Eur. J. Hum. Genet.