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Fig. 4

ID: ZDB-IMAGE-200406-193
Publication: Pei et al., 2020 - A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation
All Figures: Figures for Pei et al., 2020

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Figure Caption

Fig. 4 <italic>gemin3</italic><sup><italic>hg106</italic></sup> mutations impair regeneration of caudal fins and livers.

a Caudal fin regeneration in the control and gemin3^hg106 mutant embryos at 4 days post amputation. Arrows point to the pigment gap which is often missing in the mutants. Scale bar, 100 µm. b Quantification of the area of regenerated caudal fins in the gemin3^hg106 mutants. c Liver regeneration in the control and gemin3^hg106 mutant embryos at 3 days post ablation. The CFP fluorescence labels the regenerated livers. Scale bar, 100 µm. d Quantification of the area of the regenerated livers. Representative images are shown. Liver tissue is labeled by Tg(fabp10a:CFP-NTR). Graphs show mean ± s.e.m. **P < 0.01; ****P < 0.0001. Data for each analysis were collected from ~40 embryos produced from a pairwise heterozygous incross (for fin regeneration), or a pairwise heterozygous incross in the background of the transgene Tg(fabp10a:CFP-NTR) (for liver regeneration).

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