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Figure 8

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Publication: Zambusi et al., 2020 - Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon
All Figures: Figures for Zambusi et al., 2020

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Figure 8

Transcriptomic changes in FACS-isolated mutant oligodendroglial cells. (a–b′) Micrographs showing perfect co-localisation of DsRed in the Tg (olig2:DsRed) line with the oligodendrocyte lineage marker Sox10. (b,b′) Magnifications of the boxed areas in (a) and (a′), respectively. Scale bars: 100 µm in (a,a′) and 20 µm in (b,b′). (c) Scheme depicting isolation procedure of Olig2⁺ cells for transcriptome analysis. (d) Volcano plot of differentially regulated genes in mutant Olig2⁺ cells (padj ≤ 0.05; 1 ≤ log2FC ≤ −1). (e,f) Histograms depicting gene ontology (GO) terms enriched in the set of upregulated (e) and downregulated (f) genes in mutant Olig2⁺ cells.

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