ZFIN Image: Xu et al., 2020, Figure 6

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Figure Caption

Figure 6

Estrogen preconditioning treatment promotes zebrafish heart regenerative process. (A) Experimental design of data presented in this figure. (B) PCNA immunofluorescence (red) in the heart of male Tg (cmlc2: eGFP) zebrafish heart from regimens R1-R4. Arrowheads in the white line bounded area indicate proliferating cardiomyocytes (PCNA⁺/GFP⁺). Scale bar: 100 μm. (C) Quantification of proliferating cardiomyocytes (PCNA⁺/GFP⁺) in panel B (mean ± s.d., n = 4~5). One-way ANOVA with LSD post hoc test, *P < 0.05. (D) embCMHC immunofluorescence (red) in the male heart from regimens R1-R4. (E) Quantification of embCMHC staining in panel E (mean ± s.d., n = 5~6) in the injured area. Scale bars: 100 μm. One-way ANOVA with LSD post hoc test, *P = 0.05, ***P < 0.001.

Acknowledgments

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