ZFIN Image: Mourabit et al., 2019, Fig. 4

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Figure Caption

Fig. 4

Concentration-dependent tissue responses in Tg (3EpRE:hsp70:mCherry) zebrafish larvae exposed to cisplatin. Fish larvae were exposed to solvent control (Ai-v) and three concentrations of cisplatin (Bi-v; Ci-v; Di-v) from 2 to 4?dpf and subsequently imaged via epifluorescence and confocal microscopy. Confocal images of a lateral line neuromast labelled with SYTO24 and EpRE-mCherry expression and their colocalization, under control (Aii-v) and cisplatin exposed conditions (Bii-iv, Cii-iv, Dii-iv). Confocal images of a pronephric convoluted tubule under control (Av) and 100??M cisplatin (Dv) Arrowheads?=?neuromast; arrow?=?pronephric convoluted tubule. For images A?D, fluorescence intensity is represented using a ?Fire? lookup table with a 0?255 pixel intensity calibration bar. Nominal cisplatin culture medium concentrations displayed.

Acknowledgments

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