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Figure 1

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Publication: Yang et al., 2019 - Omics-based Investigation of Diet-induced Obesity Synergized with HBx, Src, and p53 Mutation Accelerating Hepatocarcinogenesis in Zebrafish Model
All Figures: Figures for Yang et al., 2019

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Figure 1

Overview of omics-based investigation of hepatocarcinogenesis in zebrafish models. (A) Main procedure. (B) Experimental design of omics data in zebrafish with four genetic backgrounds: WT, HBx(p53-), Src(p53-), and HBx,Src(p53-) with diet-induced obesity. (C) qPCR of some gene markers in the four models. (D) Hematoxylin and eosin (H&E) stain images of the four zebrafish models with normal diet (NOR), overfeeding (diet-induced obesity, DIO), and high-fat diet (FAT). (E) Selected differentially expressed genes (DEGs). (F) Some enriched KEGG pathways of selected DEGs. (G) Meta-z-scores of six KEGG systems of four zebrafish models.

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