ZFIN Image: Kobayashi et al., 2019, Figure 7

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Figure Caption

Figure 7

Hematopoietic differentiation in the zebrafish kidney. Schematic diagram of hematopoietic differentiation in the zebrafish kidney is shown. The orange, red, and green area denote the phenotypic transgene expression of gata2a:GFP and runx1:mCherry. Cross-hatched area shows the putative expression of gata2a:GFP and runx1:mCherry in hematopoietic progenitors. Long-term repopulating HSCs show gata2a⁺runx1⁺. In contrast, gata2a⁻runx1⁺ cells are mostly erythroid- and thrombocyte-primed progenitors, but also some myeloid-primed progenitors. Additionally, some myeloid-primed progenitors are gata2a⁺runx1⁻. Lymphoid-primed progenitors/precursors may express gata2a:GFP, but not runx1:mCherry.

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