IMAGE

Fig 5

ID

ZDB-IMAGE-191230-662

Antibodies

Ab1-myom

Source

Figures for Prill et al., 2019

Image

Figure Caption

Fig 5 Myomesin is absent in thick filament and titin mutant sarcomeres.

At 48hpf, myomesin is incorporated into the slow (perpendicular fibers) and fast (slanted fibers) muscle of wild-type siblings (A&E) while disorganized in smyd1b^tm123a (B&F), unc45b^sb60 (C&H) and titin2^tg287 (D&I) embryos. Increased magnification (40X) of muscle tissue demonstrates the sharp repeating striations of incorporated myomesin in wild-type siblings (E). Smyd1b^tm123a fast muscle (F; striations are visible in smyd1b^tm123a slow muscle, G), unc45b^sb60 (H) and titin2^tg287 (I) muscle lack myomesin striations even at 40X magnification.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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