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FIGURE 3

ID: ZDB-IMAGE-191230-66
Publication: König et al., 2019 - Distribution and Restoration of Serotonin-Immunoreactive Paraneuronal Cells During Caudal Fin Regeneration in Zebrafish
All Figures: Figures for König et al., 2019

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FIGURE 3

Characterization of HCS-cells in the adult uninjured fin. (A–C) Immunofluorescence staining of longitudinal sections of uninjured adult caudal fins; ep, epidermis, mes, mesenchyme. Dashed lines indicate the border between epidermis and mesenchyme. (A,A’) Serotonin-positive cells (green) do not express Keratin (red), which demarcates surrounding epidermal cells. (B,B’) Immunostaining for Desmoplakin (green) and Calretinin (red) indicates that Calretinin-positive cells possess very few desmosomes compared to the surrounding keratinocytes. Very weak dotty Desmoplakin staining is sometimes observed at the apical side of the cell (arrowheads). (C,C’) Staining for Serotonin (green) and Zn12 (red), a neuronal marker, reveals that cells are located close to nerve fibers. N ≥ 4 for each staining. Nuclei are labeled with DAPI (blue).

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