IMAGE

Fig. 2.

ID

ZDB-IMAGE-191230-481

Genes

GFP
mCherry

Publication

Chhabria et al., 2019 - Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish

All Figures

Figures for Chhabria et al., 2019

Image

Figure Caption

Fig. 2.

Effect of mannitol/glucose treatment with/withoutsodium nitroprusside(SNP)onklf2a:GFP expression and number of mural cellson thetectal vessels. (A) Representative micrographs of tectal vessels in Tg(klf2a:GFP) exposed to 20 mM mannitol or glucose co-treated with or without SNP. Scale bars: 20 µm. (B) Quantification of klf2a:GFP intensity in the tectal vessels (n=26 larvae/group). (C) Representative micrographs of tectal vessels showing separate and merged channels (green: fli1:GFF:UAS:GCaMP6; red: sm222ab:nls-mCherry ^sh480) for 20 mM mannitol- or glucose-exposed larvae co-treated with or without SNP. Scale bars: 20 µm. Arrows indicate mural cell nuclei. (D) Quantification of the number of sm22ab:nls-mCherry^sh480 nuclei on the tectal vessels for 20 mM mannitol- or glucose-exposed larvae co-treated with or without SNP (n=28 larvae/group). Data are mean±s.e.m. *P<0.05, **P<0.01.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.