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Figure 8
FO increases the expression of β-catenin, which translocates to the nucleus to transactivate osteogenesis-related genes. Under normal condition, β-catenin is phosphorylated by GSK-3β and consequently degraded through proteasome. FO inhibits degradation of β-catenin and increases the movement of β-catenin to nucleus. FO; fermented extract of
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