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Figure 2

ID: ZDB-IMAGE-191230-1426
Source: Figures for Azbazdar et al., 2019

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Figure Caption

Figure 2

PLM modified Wnt permits conformationally viable Fz8-PLM interaction. (A) xWnt8-Fz8-PAM complex is depicted in white. xWnt8-Fz8 are represented in cartoon, where PAM is denoted in sticks. Modeled PAM and PLM ligands (including the previously missing atoms we added) are represented in yellow sticks. (B) A close-up into the Fz8-PAM interactions. Modeled PAM cannot be aligned on the oxygen atoms of 4F0A's fatty acid. (C) PLM can direct its oxygen atoms without any problems to the serine that is modified.

Acknowledgments

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