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Fig. 5

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Publication: Gómez-Abenza et al., 2019 - Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment
All Figures: Figures for Gómez-Abenza et al., 2019

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Fig. 5

Spint1a deficiency both in stromal and tumor cell enhances SKCM dissemination in zebrafish larval model. a Allotransplant experimental design. Combinations of Spint1a-deficient tumor and stromal cells from SKCMs were mixed with wild type tumor and stromal cells. All possible cell combinations were obtained maintaining the initial ratio. b Representative images (overlay of bright field and red channels) of the invasion in wild type recipient larvae at 5 dpi. Bar: 500 μm. c Number of tumor foci per larva (n = 5 SKCM tumors). **p < 0.01 according to a Chi-square Test

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