Figure 8

Figure 8

A dilution range reveals specific effects of compactin and verrucarin A on zebrafish embryogenesis. Zebrafish embryos were treated with different concentrations of (A–E) compactin or (F–J) verrucarin A from 6 hpf onwards and were imaged at 48 hpf. (A) 100 nM, (B) 50 nM, (C) 25 nM, (D), 10 nM, (E) 5 nM compactin. (F) 60 nM, (G) 50 nM, (H) 40 nM, (I) 30 nM, (J) 20 nM verrucarin A. Higher concentrations of compactin or verrucarin A were lethal.