ZFIN Image: Aleksandar et al., 2019, Fig. S4

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Figure Caption

Fig. S4

The toxicity evaluation of doxorubicin (Dox) and A. flavum and A. carinatum extracts in zebrafish embryos expressed as the LC₅₀ values. Data are presented as the mean ± SE of three independent experiments with 20 embryos per concentration. Morphology of zebrafish embryos at 96 hpf exposed to 30 µg/mL of A. flavum and A. carinatum extracts (normal embryos) and 10 µg/mL Dox (seriously malformed embryos) are shown. Embryos upon 10 µg/mL of Dox suffered from large pericardial edema (arrow) and body edema (empty arrowhead), were reduced in the growth and yolk consumption (asterisk), had malformed head (bracket), jaw (dashed arrow) and otoliths (boxed), and scoliosis (black arrowhead)

Acknowledgments

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