ZFIN Image: Vázquez-Marín et al., 2019, Fig. 7

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Figure Caption

Fig. 7

yap1/yap1b relative regulatory weight and yap1b rescuing capacity. (A) Quantification of the expression levels of genes targeted by Yap family proteins in wild-type, yap1^−/− and yap1b^−/−medaka embryos (stage 16) by qPCR (n=3). Comparative dorsal (B-E) and lateral (B′-E′) views of stage 24 medaka embryos in yap1b rescuing experiments. Embryo genotype (either yap1^+/+ or yap1^−/−) and yap1b injections are indicated. Embryo flattening (double-headed arrows) and optic cup shape (dotted lines) are also highlighted. The complete yap1^−/− phenotypic rescue upon yap1b mRNA injection (E). One-way ANOVA analysis followed by Fisher's LSD test was used to evaluate statistical significance. ***P<0.001; **P<0.01; *P<0.05; ns, not significant.

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