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Fig. 4
crestin:EGFP turns on at 9–12 weeks of age. Two examples of casper;mcr:NRAS;crestin:EGFP zebrafish at 4–16 weeks post-fertilization. The crestin:EGFP transgene appears to be activated at between 9 and 12 weeks of age. Scale bars represent 1000 µm for all images.
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Reprinted from Developmental Biology, 449(2), McConnell, A.M., Mito, J.K., Ablain, J., Dang, M., Formichella, L., Fisher, D.E., Zon, L.I., Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion, 107-114, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.