ZFIN Image: Wafer et al., 2017, Figure 2

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Figure 2

Extensive shared synteny between mammals and fish at the Peroxisome proliferator-activated receptor (PPARG) locus. The predicted ancestral locus was inferred from comparing the loci documented in the figure, together with the chondrichthyan elephant shark (Callorhinchus milii) locus (not shown). The C. milii locus contained Cenp and Rab43 genes (indicated with an asterisk). Ts3R indicates the teleost-specific genome duplication. Note the inversion of TIMP4 and SYN2 upstream of PPARG in the mammalian lineage. Duplicated raf1 paralogs (raf1a and raf1b) are only retained in zebrafish and cavefish.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Endocrinol (Lausanne)