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Figure 3
Network diagram showing the cellular functions of OCRL1. OCRL1 interaction partners are shown in green, and associated functions are indicated in blue boxes. Purple boxes highlight the two universal processes that are influenced by OCRL1, namely membrane trafficking and actin cytoskeleton remodeling. Both are relevant for all the functions shown in blue, and are linked accordingly. Note the diagram is not exhaustive, and some of the OCRL1-binding partners are likely to participate in several of the processes indicated. Although endocytosis and endocytic recycling are types of membrane trafficking, they are also shown separately as distinct processes given their reliance on different OCRL1-binding proteins.