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Figure 1
Schematic diagram showing the organs affected in Lowe syndrome. Oculocerebrorenal syndrome of Lowe affects the eyes, central nervous system and kidneys, with specific manifestations in each organ as indicated. Dent-2 affects the same organs and displays similar manifestations, although the ocular and neurological defects are typically milder than those seen in Lowe syndrome. Renal tubular acidosis is also less frequently observed in Dent-2 disease.
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